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The effect of addition of ketamine, lidocaine and ?acetaminophen and dexmedetomidine to morphine in the pain control of opium addicts

Comparison of the effect of addition of Ketamine, Lidocaine, Acetaminophen and Dexmedetomidine to morphine in the pain control of opium addicts after orthopedic surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141209020258N146
Enrollment
140
Registered
2020-07-10
Start date
2020-05-21
Completion date
Unknown
Last updated
2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain after orthopedic surgery. Encounter for orthopedic aftercare following scoliosis surgery

Interventions

Intervention 1: Intervention group 1: 1 mg/kg of Ketamine (produced by Rotex Medica company, Germany) will be added to morphine. Intervention 2: Intervention group 2: 15 mg/kg of Acetaminophen (produc

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age of 20 to 60 years old ASA class 1 and 2

Exclusion criteria

Exclusion criteria: Dissatisfaction with studying Not accepting spinal anesthesia as a method of anesthesia Obesity Chronic pain Mental disorders History of seizures Use psychotropic drugs Use of painkillers (more than a week) Sensitivity to drugs Upper respiratory infection Pregnancy Breastfeeding Existence of hemodynamic instability

Design outcomes

Primary

MeasureTime frame
Relaxation. Timepoint: At 1, 6, 12 and 24 hours after connecting the pump. Method of measurement: Ramsy score.;Average drug use. Timepoint: 24 hours after connecting the pump. Method of measurement: Observation.;Nausea and vomiting. Timepoint: At 1, 6, 12 and 24 hours after connecting the pump. Method of measurement: Observation.;Pain. Timepoint: At 1, 6, 12 and 24 hours after connecting the pump. Method of measurement: Visual pain analog scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Esmaeel Moshiri

Arak University of Medical Sciences

modir.he@gmail.com+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 11, 2026