Skip to content

Comparison of magnesium sulfate and dexmedetomidine and ondansetron ?supplementation with lidocaine for pre-laryngoscopic and tracheal intubation ?gargling in prevention of sore throat and control of hemodynamic changes

Comparison of magnesium sulfate and dexmedetomidine and ondansetron ?supplementation with lidocaine for pre-laryngoscopic and tracheal intubation ?gargling in prevention of sore throat and control of hemodynamic changes

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141209020258N145
Enrollment
105
Registered
2020-07-05
Start date
2020-04-18
Completion date
Unknown
Last updated
2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sore throat. Acute pharyngitis, unspecified

Interventions

Intervention 1: Intervention group: Patients will grunt 2 gram Magnesium Sulfate 20 percent (Shahid ghazi Co) plus 100 milligram Lidocaine and 5 millilitre Dextrose 20 percent. Intervention 2: Interve

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 60 Years

Inclusion criteria

Inclusion criteria: 30 to 60 years ASA class 1 and 2 No history of sore throat before surgery No history of head and neck surgery, especially of the throat No history of drug use No history of chronic housing use Lack of sensitivity to the drugs used in this study Lack of upper airway infection and cold Malampati more than 2 Lack of liver and kidney failure No need to use NG-tube during surgery and up to 24 hours after surgery The duration of surgery should not be less than 45 minutes and not more than 120 minutes

Exclusion criteria

Exclusion criteria: Patient dissatisfaction with continuing to study Observation of blood during suction when removing the tracheal tube For whatever reason, we have to have laryngoscopy twice

Design outcomes

Primary

MeasureTime frame
Sore throat. Timepoint: In recovery and 2, 4, 8, 12 and 24 hours after surgery. Method of measurement: Observation.;Hoarseness. Timepoint: In recovery and 2, 4, 8, 12 and 24 hours after surgery. Method of measurement: Observation.;Cough. Timepoint: In recovery and 2, 4, 8, 12 and 24 hours after surgery. Method of measurement: Observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Shirin Pazuki

Arak University of Medical Sciences

pazuki@arakmu.ac.ir+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026