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Immunomodulatory effect of an herbal supplement containing Fenugreek, Nigella sativa ?and Sumac in patients with type 2 diabetes

Immunomodulatory effect of an herbal supplement containing Fenugreek, Nigella sativa ?and Sumac in patients with type 2 diabetes

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141209020258N144
Enrollment
72
Registered
2020-06-27
Start date
2020-05-05
Completion date
Unknown
Last updated
2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type II diabetes. Diabetes mellitus due to underlying condition

Interventions

Intervention 1: Intervention group: In addition to the usual treatments for diabetes we treat patients with 6 capsules containing 3 Nigella sativa daily at a dose of 170 milligram, Fenugreek with a do

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 50 Years

Inclusion criteria

Inclusion criteria: Fasting blood sugar is equal to or higher than 126 milligram per millileter Taking oral hypoglycemic drugs Consumption of a fixed dose of oral hypoglycemic drugs for at least the last 3 months Lack of kidney failure Lack of type 1 diabetes Lack of acute and chronic inflammatory diseases Lack of malignancy Lack of drug addiction No pregnancy or lactation

Exclusion criteria

Exclusion criteria: Dissatisfaction

Design outcomes

Primary

MeasureTime frame
Cytokine TGF-ß. Timepoint: Before intervention and 6 weeks after the treatment. Method of measurement: Blood test.;Cytokine TNF?. Timepoint: Before intervention and 6 weeks after the treatment. Method of measurement: Blood test.;Cytokine IFN-?. Timepoint: Before intervention and 6 weeks after the treatment. Method of measurement: Blood test.;Cytokine IL-17. Timepoint: Before intervention and 6 weeks after the treatment. Method of measurement: Blood test.;Number of Treg cells. Timepoint: Before intervention and 6 weeks after the treatment. Method of measurement: Blood test.;Nitric oxide measurement. Timepoint: Before intervention and 6 weeks after the treatment. Method of measurement: Blood test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mehdi Salehi

Arak University of Medical Sciences

m.salehi@arakmu.ac.ir+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026