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The effects of Melatonin, Gabapentin and Dextromethorphan on post operative pain control in patients undergoing hip fracture surgery with general anesthesia

The effects of Melatonin, Gabapentin and Dextromethorphan on post operative pain control in patients undergoing hip fracture surgery with general anesthesia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141209020258N136
Enrollment
120
Registered
2020-03-13
Start date
2020-01-21
Completion date
Unknown
Last updated
2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip fracture surgery. Fracture of acetabulum

Interventions

Intervention 1: Intervention group 1: We treat patients with 6 milligram Melatonin sublingual (Webber Natural.Canadian Co.) dissolved in water (final volume is 5 millimeter ) 90 minute before surgery.

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
17 Years to 65 Years

Inclusion criteria

Inclusion criteria: Candidate for hip fracture surgery 17 to 65 years old Both sexes Absence of fractures in other organs Absence of coagulation disorders Lack of renal and hepatic and cardiovascular disease No history of drug use in the past 48 hours No drug and psychotropic addiction and alcohol

Exclusion criteria

Exclusion criteria: Unwillingness to participate in the study Severe hemodynamic instability

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: At recovery time, 2, 4, 6, 12 and 24 hours after surgery. Method of measurement: Visual analog scale.;Sedation. Timepoint: 24 hours after surgery. Method of measurement: Ramsy score.;Mean of opiate drug. Timepoint: 24 hours after surgery. Method of measurement: Milligram.;Mean blood pressure. Timepoint: Every 15 minutes during surgery and recovery time. Method of measurement: Barometer.;Mean heart rate. Timepoint: Every 15 minutes during surgery and recovery time. Method of measurement: Count.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Behnam Mahmodie

Arak University of Medical Sciences

mahmodie@arakmu.ac.ir+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026