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Effect of combination of Propofol-Remifentanil vs Ketofel in duration of seizure and hemodynamic signs of psychotics patient in electroconvulsive therapy

Effect of combination of Propofol-Remifentanil versus Ketofel in duration of seizure and hemodynamic signs of psychotics patient in electroconvulsive therapy

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141209020258N129
Enrollment
105
Registered
2020-01-12
Start date
2019-05-05
Completion date
Unknown
Last updated
2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

psychotics patient. Psychotic disorder with hallucinations due to known physiological condition

Interventions

Intervention 1: Intervention group1: We will inject Remifentanil 1 milligram in kilogram (Produced by Normon Company) and Propofol 1 milligram in kilogram. Intervention 2: Intervention group2: We will

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 18 to 50 years Patients with a diagnosis of major schizophrenia depression of catatonia or bipolar disorder ASA class I and II

Exclusion criteria

Exclusion criteria: Sensitivity to medications used Drug history History of cardiovascular disease Pregnancy Patients in need of treatment for hemodynamic instability following seizures, who had less than 25 second tonic or clonic seizures, or had more than 60% energy to induce seizures

Design outcomes

Primary

MeasureTime frame
Mean arterial pressure. Timepoint: At baseline, 1, 2, and 3 minutes after shock and after recovery. Method of measurement: Barometer.;Heart rate. Timepoint: At baseline, 1, 2, and 3 minutes after shock and after recovery. Method of measurement: Count.;Oxygen saturation percentage. Timepoint: At baseline, 1, 2, and 3 minutes after shock and after recovery. Method of measurement: Pulse oximetry.;Duration of seizures. Timepoint: After electro convulsive therapy. Method of measurement: Minute.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Hesamedin Modir

Arak University of Medical Sciences

modir.he@gmail.com+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026