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Comparison of the effect of adding Dexmedetomidine, Granisetron and Nitroglycerin to Rupivacaine in Reducing Pain and Hemodynamic Changes in intravenous regional anesthesia of forearm surgery

Comparison of the effect of adding Dexmedetomidine, Granisetron and Nitroglycerin to Rupivacaine in Reducing Pain and Hemodynamic Changes in intravenous regional anesthesia of forearm surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141209020258N123
Enrollment
128
Registered
2019-11-02
Start date
2019-07-23
Completion date
Unknown
Last updated
2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

forearm surgery. Unspecified fracture of forearm

Interventions

Intervention 1: Intervention group: We will inject 0/5 micro gram in kilogram co.Dexmedetomidine (Exir Co.Iran) plus 35 milliliter Rupivacaine 0/2%(Molteni Co.Italia). Intervention 2: Intervention gro

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Both of gender 20 to 65 years Candidate forearm surgery ASA class I and II

Exclusion criteria

Exclusion criteria: Rinod's disease Sickle cell anemia History of allergy to the drugs used in the study Affected limb cyanosis Drugs and psychotropic use There is more than one body fracture or surgery Pregnancy Chronic pain syndrome Neurological disorders in the hand Hypertension-related disease and heart erythema and heart failure

Design outcomes

Primary

MeasureTime frame
Duration of motor block. Timepoint: Every 5 minute. Method of measurement: Minute.;Duration of Sensory block. Timepoint: Every 1 minute. Method of measurement: Minute.;Pain. Timepoint: After filling the tourniquet, at the time of 15, 30 and 45 and every 15 minutes until the end of surgery. Method of measurement: Visual Analogue Scale Questionnaire.;Mean use of narcotic. Timepoint: 24 hour after surgery. Method of measurement: Milligram.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Hesamedin Modir

Arak University of Medical Sciences

modir.he@gmail.com+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 14, 2026