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Comparison of the effects of administration of intrathecal dexmedetomidine and fentanyl ?and magnesium sulfate as adjuvant to ropivacaine in duration and onset of sensory and ?motor block in lower abdominal surgery

Comparison of the effects of administration of intrathecal dexmedetomidine and fentanyl ?and magnesium sulfate as adjuvant to ropivacaine in duration and onset of sensory and ?motor block in lower abdominal surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141209020258N118
Enrollment
90
Registered
2019-07-27
Start date
2019-03-06
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lower abdominal surgery. During surgical operation

Interventions

Intervention 1: Intervention group: We will inject 3 milliliter (15 milligram) Rupivacaine plus 10 micro gram Dexmedetomidine (1 milliliter) Intrathecal. Intervention 2: Intervention group: We will in

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 18 to 60 years Patients candidate lower abdominal surgery Lack of body mass index less than 30

Exclusion criteria

Exclusion criteria: Failure to perform spinal anesthesia Dissatisfaction History of taking beta-blockers and alpha-2 calcium channel blockers and blockers Cardiovascular problems Arrhythmia Mental and psychological problems Peripheral and central neuropathy

Design outcomes

Primary

MeasureTime frame
Mean arterial blood pressure. Timepoint: Every 15 minutes during surgery and recovery time. Method of measurement: Digital sphygmomanometer.;Heart rate. Timepoint: Every 15 minutes during surgery and recovery time. Method of measurement: ECG.;Percent of oxygen saturation. Timepoint: Every 15 minutes during surgery and recovery time. Method of measurement: Pulse oximetry.;Duration of motor block. Timepoint: Every 5 minute. Method of measurement: chronometer.;Duration of sensory block. Timepoint: Every 1 minute. Method of measurement: chronometer.;Pain. Timepoint: Recovery and 1, 2, 4, 6,12 and 24 hours after surgery. Method of measurement: Visual Analogue Scale Questionnaire.;Mean of narcotic. Timepoint: 24 hour after surgery. Method of measurement: Observation amount of opiate consumed.—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Afsaneh Noruzi

Arak University of Medical Sciences

dr.noruzi@arakmu.ac.ir+98 86 3471 3638

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026