Comparison of the effect of adding Neostigmine to Ropivacaine and sufentanilto Ropivacaine in spinal anesthesia for herniorrhaphy surgery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141209020258N107

Enrollment

105

Registered

2019-04-23

Start date

2019-03-01

Completion date

Unknown

Last updated

2019-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal anesthesia. Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances

Interventions

Intervention 1: Intervention group: We inject 3 milliliter of Ropivacaine(15 milligram) plus 50 micro gram Neostigmine (Caspian.Co.Rasht)(1 milliliter) in form of intrathecal. Intervention 2: Interven

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 18 to 60 years Patients candidate inguinal hernia surgery Lack of cardiovascular problems Absence of coagulation disorders Lack of peripheral and central neuropathy No history of allergy to Neostigmine and Ropivacaine and Sufentanil Non-localized infection in the spinal cord

Exclusion criteria

Exclusion criteria: Patient dissatisfaction Failure to perform spinal anesthesia

Design outcomes

Primary

Measure	Time frame
Mean arterial blood pressure. Timepoint: Every 15 minutes during surgery and recovery time and up to 2 hours after surgery. Method of measurement: Barometer.;Heart rate. Timepoint: Every 15 minutes during surgery and recovery time and up to 2 hours after surgery. Method of measurement: Count.;Percent of oxygen saturation. Timepoint: Every 15 minutes during surgery and recovery time and up to 2 hours after surgery. Method of measurement: Pulse oximetry.;Duration of motor block. Timepoint: Every 5 minute. Method of measurement: Minute.;Duration of Sensory block. Timepoint: Every 1minute. Method of measurement: Minute.;Pain. Timepoint: Recovery and 2, 4, 8, 12 and 24 hours after surgery. Method of measurement: Visual Analogue Scale Questionnaire.;Mean of narcotic. Timepoint: 24 hour after surgery. Method of measurement: Milligram.	—

Measure

Time frame

Mean arterial blood pressure. Timepoint: Every 15 minutes during surgery and recovery time and up to 2 hours after surgery. Method of measurement: Barometer.;Heart rate. Timepoint: Every 15 minutes during surgery and recovery time and up to 2 hours after surgery. Method of measurement: Count.;Percent of oxygen saturation. Timepoint: Every 15 minutes during surgery and recovery time and up to 2 hours after surgery. Method of measurement: Pulse oximetry.;Duration of motor block. Timepoint: Every 5 minute. Method of measurement: Minute.;Duration of Sensory block. Timepoint: Every 1minute. Method of measurement: Minute.;Pain. Timepoint: Recovery and 2, 4, 8, 12 and 24 hours after surgery. Method of measurement: Visual Analogue Scale Questionnaire.;Mean of narcotic. Timepoint: 24 hour after surgery. Method of measurement: Milligram.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Alireza Kamali

Arak University of Medical Sciences

alikamaliir@yahoo.com+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026