Comparison of the effect of salbutamol and diphenhydramine prodrugs on the incidence rate of adverse respiratory events in the examination under the ophthalmologic of children with colds under anesthesia.

Comparison of the effect of salbutamol and diphenchidramine prejudice on adverse respiratory events in children with colds during anesthesia: a randomized clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141209020253N1

Enrollment

200

Registered

2025-01-16

Start date

2025-01-19

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

common cold. Acute nasopharyngitis [common cold]

Interventions

Intervention 1: Intervention group: Half an hour before the operation, in the diphenhydramine group (100 people), diphenhydramine compound syrup 5cc (age 3 to 7 years) is administered. Induction of an

Eligibility

Sex/Gender

All

Age

3 Years to 7 Years

Inclusion criteria

Inclusion criteria: Age 3-7 years Patients who need urgent ophthalmologic examination under anesthesia catching cold Filling out the patient's informed consent form

Exclusion criteria

Exclusion criteria: Unwillingness to participate in the study The need for non-eye surgery

Design outcomes

Primary

Measure	Time frame
Laryngospasm. Timepoint: during induction, during operation and after operation and 4 hours after operation in recovery. Method of measurement: monitoring.;Bronchospasm. Timepoint: during induction, during operation and after operation and 4 hours after operation in recovery. Method of measurement: monitoring.;Saturation drop. Timepoint: during induction, during operation and after operation and 4 hours after operation in recovery. Method of measurement: monitoring.	—

Measure

Time frame

Laryngospasm. Timepoint: during induction, during operation and after operation and 4 hours after operation in recovery. Method of measurement: monitoring.;Bronchospasm. Timepoint: during induction, during operation and after operation and 4 hours after operation in recovery. Method of measurement: monitoring.;Saturation drop. Timepoint: during induction, during operation and after operation and 4 hours after operation in recovery. Method of measurement: monitoring.

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Secondary

Measure	Time frame
Cough. Timepoint: during induction, during operation and after operation and 4 hours after operation in recovery. Method of measurement: monitoring.;Spasm. Timepoint: during induction, during operation and after operation and 4 hours after operation in recovery. Method of measurement: monitoring.;Bucking. Timepoint: during induction, during operation and after operation and 4 hours after operation in recovery. Method of measurement: monitoring.;Airway pressure. Timepoint: during induction, during operation and after operation and 4 hours after operation in recovery. Method of measurement: monitoring.;The amount of restlessness. Timepoint: during induction, during operation and after operation and 4 hours after operation in recovery. Method of measurement: monitoring.	—

Measure

Time frame

Cough. Timepoint: during induction, during operation and after operation and 4 hours after operation in recovery. Method of measurement: monitoring.;Spasm. Timepoint: during induction, during operation and after operation and 4 hours after operation in recovery. Method of measurement: monitoring.;Bucking. Timepoint: during induction, during operation and after operation and 4 hours after operation in recovery. Method of measurement: monitoring.;Airway pressure. Timepoint: during induction, during operation and after operation and 4 hours after operation in recovery. Method of measurement: monitoring.;The amount of restlessness. Timepoint: during induction, during operation and after operation and 4 hours after operation in recovery. Method of measurement: monitoring.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahtab Poorzmani Nejat Kermani

Shahid Beheshti University of Medical Sciences

drpoorzamani@yahoo.com+98 21 2360 2175

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026