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The comparison of two regimens of diphencyprone in alopecia areata patients.

Evaluation and comparison of the efficacy and safety of two regimens of diphencyclopropenone (applying different concentrations to identify the effective concentration vs. traditional method) in the treatment of alopecia areata in patients referred to Razi Hospital, 1398-1399.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141209020250N5
Enrollment
60
Registered
2019-11-24
Start date
2019-11-22
Completion date
Unknown
Last updated
2019-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

alopecia areata. Alopecia areata

Interventions

Intervention 1: Intervention group1: 30 patients with alopecia areata who are receiving topical diphencyprone with new regimen. Intervention 2: Intervention group 2: 30 patients with alopecia areata

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with alopecia areata Possibility of regular visit for the patient Hair loss more then 50 % The age of the patient greater than 18 years old

Exclusion criteria

Exclusion criteria: Pregnancy and lactation Persistent totalis or universalis areata alopecia from infancy Prominent androgenetic alopecia No response to diphencyprone test Patients with hematologic dysplasia receiving systemic immunosuppressive therapy during recent 3 months

Design outcomes

Primary

MeasureTime frame
Terminal hair regrowth rate with topical diphencyprone with old regimen in comparison to new regimen in patients with alopecia areata, based of SALT score. Timepoint: before intervention and 3 and 6 months after intervention. Method of measurement: Severity of Alopecia Tool Score.

Secondary

MeasureTime frame
Rate of change in Severity of Alopecia Tool score than the base value, after intervention and at the end of course of treatment. Timepoint: 3 and 6 months after treatment. Method of measurement: Severity of Alopecia Tool score.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDoctor Alaa Al Bazzal

Tehran University of Medical Sciences

alabazal9@gmail.com+98 21 5560 9951

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 20, 2026