Skip to content

?Allopurinol prescription for better control of blood pressure

The effect of allopurinol on serum uric acid level and arterial blood pressure in hemodialysis patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014120820243N1
Enrollment
146
Registered
2015-01-03
Start date
2014-12-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: hypertension. Condition 2: hyperuricemia. Hypertensive renal disease with renal failur Asymptomatic hyperuricaemia

Interventions

Intervention 1: Intervention group:they get Allopurinpl 100 mg one tablet daily for three months with meal(lunch ordinner). Intervention 2: control:multivitamine one tablet daily for three months.
Treatment - Drugs
Intervention group:they get Allopurinpl 100 mg one tablet daily for three months with meal(lunch ordinner)
control:multivitamine one tablet daily for three months

Sponsors

Kermanshah University of Medical Mciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria:Hypertension? hyperuricemia? patients must be on dialysis since at least 3 month ago? no taking diuretics?no taking other uric acid lowering agents?have signed the informed consent. Exclusion criteria:irregular use of the drug?presence of severe adverse effects

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Blood pressure. Timepoint: before intervention,one and two and three months after begining. Method of measurement: by mercury barometer in scale of mm Hg.;Uric acid. Timepoint: Before intervention 1,2 and 3 months later. Method of measurement: by blood sampling.

Secondary

MeasureTime frame
The drug side effects. Timepoint: Before intervention 1,2 and 3 months later. Method of measurement: clinical manifestations and CBC.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Mohammad kazem Sadeghi

Kermanshah University Of Medical Sciences

smk.sadeghi@kums.ac.ir smksadeghi9@gmail.com+98 83 3427 6309

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026