type 2 diabetes mellitus with coronary artery disease. non insulin dependent diabetes mellitus
Conditions
Interventions
Intervention 1: Continuous aerobic training: 30 minutes walking on a treadmill and 30 minutes of cycling on an upright bike with moderate intensity (50-70% VO2max). Total training duration of 60 minut
Lifestyle
Continuous aerobic training: 30 minutes walking on a treadmill and 30 minutes of cycling on an upright bike with moderate intensity (50-70% VO2max). Total training duration of 60 minutes.
High intensity interval training (HIIT): Subjects will train on cycling ergometer which last for 10 minute duration. They will start with gradual incremental intensity training for 6 minutes (maximum
Combined aerobic with resistance training: Continuous 30 minutes walking on a treadmill and 30 minutes of cycling on an upright bike at moderate intensity (50-70% VO2max). Then they have to do resista
Sponsors
University Malaya Research Grant (UMRG)
Eligibility
Sex/Gender
All
Age
36 Years to 74 Years
Inclusion criteria
Inclusion criteria: Patients who fulfill the inclusion and exclusion criteria as listed below are recruited: Inclusion criteria for the subjects are patients with type 2 diabetes mellitus with coronary artery disease co-morbidity manifested by one or more of these: -Ischemic Heart Disease, but no current angina -Post angioplasty / stenting or post coronary artery bypass surgery -Stable pharmacological therapy -Chronic Heart Failure New York Association (NYHA I, II and III) in the absence of congestive heart failure at the time of study Patients with the listed criteria are excluded from the study: -Myocardial Infarction, Cardiac arrest, symptomatic or sustained ventricular tachycardia in the previous 6 months -Unstable heart failure, or NYHA Class IV patients -Symptomatic or sustained ventricular tachycardia -Current angina or baseline assessment suggesting unsatisfactory control of heart failure -Current acute musculoskeletal event and/or neurological impairments that adversely affect exercise capacity. -Any other symptoms that prevent the patients from exercising.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HbA1c (glycated haemoglobin). Timepoint: 12 weeks following end of treatment. Method of measurement: Blood sample laboratory test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Body composition. Timepoint: 12 weeks following end of treatment. Method of measurement: bioelectrical impedance analysis machine.;Lipid profile. Timepoint: 12 weeks following end of treatment. Method of measurement: Blood sample laboratory test.;Fasting blood glucose. Timepoint: 12 weeks following end of treatment. Method of measurement: Blood sample laboratory test.;Maximum oxygen consumption (VO2max). Timepoint: 12 weeks following end of treatment. Method of measurement: cycling ergometer using Astrand or Naughton protocol. | — |
Countries
Malaysia
Contacts
Public ContactMoriffin Mahpis
University Malaya Medical Centre
Outcome results
None listed