Depression. Depressive episode
Conditions
Interventions
Intervention 1: Intervention group: Vitamin D pearl, 50000 IU, weekly, for 8 weeks orally. Intervention 2: Control group: Placebo pearl, weekly, for 8 weeks orally.
Sponsors
Kashan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients with major depressive according to DSM-IV-TR criteria Aged 18 to 65 years The least score 15 on Hamilton Depression scoring system.
Exclusion criteria
Exclusion criteria: History of coronary infarction, angina pectoris, stroke or renal stone disease Pregnant or lactating women Smokers Liver problems Substance abuse Non-normal creatinine concentrations Taking dietary supplements during the last 2 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression. Timepoint: At the beginning of the study and after 8 weeks of intervention. Method of measurement: Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Fasting plasma glucose. Timepoint: Baseline and End-of-trial. Method of measurement: Enzymatic.;Triglycerides. Timepoint: Baseline and End-of-trial. Method of measurement: Enzymatic.;Total antioxidant capacity. Timepoint: Baseline and End-of-trial. Method of measurement: Spectrophotometry.;Glutathione. Timepoint: Baseline and End-of-trial. Method of measurement: Spectrophotometry.;Cholesterol. Timepoint: Baseline and End-of-trial. Method of measurement: Enzymatic.;Insulin. Timepoint: Baseline and End-of-trial. Method of measurement: Elisa. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZatollah Asemi
Kashan University of Medical Sciences
Outcome results
None listed