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The comparison of analgesic effects of epidural and TAP block

The comparison of analgesic and opioid- sparing effects of a preemptive single-shot epidural analgesia and unilateral single-injection Transversus Abdominis Plane block in patients undergoing renal sugeries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201412063436N4
Enrollment
80
Registered
2015-02-17
Start date
2015-02-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Acute post-operative pain. Condition 2: nephrectomy. Acute pain acquired absence of kidney

Interventions

Intervention 1: Lumbar epidural catheter placement and injection a total volume of15cc including 4cc bupivacaine 0.5% and 11cc pure water before induction of anesthesia. Intervention 2: perform unilat
Prevention
Lumbar epidural catheter placement and injection a total volume of15cc including 4cc bupivacaine 0.5% and 11cc pure water before induction of anesthesia
perform unilateral TAP block at the site of surgery and injection a total volume of15cc including 4cc bupivacaine 0.5% and 11cc pure water after induction of anesthesia and 10 minutes before surgical

Sponsors

Anesthesiology Research Center, Labbafinejad Hospital, 9th Boostan, Pasdaran, Tehran, Iran
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria would be as follows: 1- ASA class I to II 2- Renal surgeries including open nephrectomy, radical nephrectomy, open surgery for renal or ureteral stones. Exclusion criteria are as follows: 1- Long lasting surgery (more than three hours) 2- Chronic use of opioid 3- Complications such as severe hemorrhage 4- Intractable nausea and vomiting 5- Two episodes of intractable pain 6- More drug prescriptions other than protocol 7- Difficult airway 8- Drug allergy 9- Diabetes mellitus, Pregnancy, morbid obesity

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Post operative pain. Timepoint: 24 hours after sugery. Method of measurement: VRS(Verbal Rating Scale).;Opioid use after surgery. Timepoint: 24 hours after sugery. Method of measurement: mg.

Secondary

MeasureTime frame
Bradypnea (RR <10). Timepoint: after opioid use. Method of measurement: continuous observation.;Itching. Timepoint: after opioid use. Method of measurement: observation.;Vomiting. Timepoint: after opioid use. Method of measurement: observation.;Hemorrhage during surgery. Timepoint: after intervention,during surgery. Method of measurement: observation (ml).;Hospital stay. Timepoint: after intervention. Method of measurement: patient file information.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBabak Gharaei

Anesthesiology Research Center , Labbafinejad Hospital, 9th Boostan, Pasdaran, Tehran, Iran

babakgharaei@gmail.com+98 21 2360 2175

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026