Mucositis. Oral mucositis (ulcerative)
Conditions
Interventions
Intervention 1: Intervention group 1: 4 gram Sachets of Malva sylvestris & Alcea digitata compound (2 grams of each Herb)
For 7 weeks
3 times daily after meals. Intervention 2: Control Group: 4 gram Sachets of Avecil
3 times a day, after meals.
Treatment - Drugs
Placebo
Intervention group 1: 4 gram Sachets of Malva sylvestris & Alcea digitata compound (2 grams of each Herb)
3 times daily after meals
Control Group: 4 gram Sachets of Avecil
3 times a day, after meals
Sponsors
Vice Chancellor for research of Shahed University
Eligibility
Sex/Gender
All
Age
17 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients with 17-65 years old in both sexes; candidate for radiotherapy for head & neck cancers; life expectancy over 1 year; Good performance status in ECOG questionnaire; At least 4 areas in RT fields Early Exclusion criteria: Patients with organic & suppressive disorders; Use of drugs effective on salivary glands, cigar or alcohol; History of Rt in last 6 months; Grade 3-4 Mucositis, candidiasis, oral herpes; Failure to treat, Hospitalization or need to TPN; Lack of interest in work
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mucositis. Timepoint: At the baseline, Weeks 1,2,3,4,5,6,7. Method of measurement: Examination of Oral Cavity.;Pain. Timepoint: At the baseline, Weeks 1,2,3,4,5,6,7. Method of measurement: Visual Analogue Scale.;Quality of Life. Timepoint: Weeks 1,2,3,4,5,6,7. Method of measurement: EORTC questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side Effects. Timepoint: Weeks 1,2,3,4,5,6,7. Method of measurement: Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNasser Rezaeipour
Shahed University of Medical Sciences
Outcome results
None listed