Effect of Ziziphus fruit in type 2 diabetic patients

Effect of Ziziphus fruit on lipid profile and blood glucose in type 2 diabetic patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014120510826N15

Enrollment

116

Registered

2014-12-19

Start date

2014-08-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 2 diabetes. Non-insulin-dependent diabetes mellitus

Interventions

Intervention 1: Intervention group: providing a diet plan with a 500 kcal/d deficit calculated from the Harris Benedict formula adjusted for sex and activity. they also use 30 gr ziziphus fruit ( to b

Intervention group: providing a diet plan with a 500 kcal/d deficit calculated from the Harris Benedict formula adjusted for sex and activity. they also use 30 gr ziziphus fruit ( to brewed) daily for

Control group: providing a diet plan with a 500 kcal/d deficit calculated from the Harris Benedict formula adjusted for sex and activity at 12-week intervals.

Eligibility

Sex/Gender

All

Age

30 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: type 2 diabetic patients with body mass index>=25; individuals older than 30 years old; HbA1c less than 9.5; do not change in drugs during the intervention; do not use ziziphus fruit in the last 4 weeks; individuals who do not participate in another intervention; do not inject insulin. Exclusion criteria: lack of desire to continue study; have any other diseases like liver, renal and cancer disease; no use more than 30% of ziziphus fruit; individuals who suffer from diabetes more than 10 years.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
2-Hour Post-Prandial Blood Glucose. Timepoint: before the intervention and 12 weeks after the intervention. Method of measurement: blood biochemical tests.;Fasting blood sugar. Timepoint: before the intervention and 12 weeks after the intervention. Method of measurement: blood biochemical tests.;Hemoglobin A1c. Timepoint: before the intervention and 12 weeks after the intervention. Method of measurement: blood biochemical tests.;Total cholestrol. Timepoint: before the intervention and 12 weeks after the intervention. Method of measurement: blood biochemical tests.;Triglyceride. Timepoint: before the intervention and 12 weeks after the intervention. Method of measurement: blood biochemical tests.;Low density lipoprotein. Timepoint: before the intervention and 12 weeks after the intervention. Method of measurement: blood biochemical tests.;High density lipoprotein. Timepoint: before the intervention and 12 weeks after the intervention. Method of measurement: blood biochemical tests.;Added at 2016-09-16: MDA. Timepoint: Added at 2016-09-16: before the intervention and 12 weeks after the intervention. Method of measurement: Added at 2016-09-16: blood biochemical tests.	—

Measure

Time frame

2-Hour Post-Prandial Blood Glucose. Timepoint: before the intervention and 12 weeks after the intervention. Method of measurement: blood biochemical tests.;Fasting blood sugar. Timepoint: before the intervention and 12 weeks after the intervention. Method of measurement: blood biochemical tests.;Hemoglobin A1c. Timepoint: before the intervention and 12 weeks after the intervention. Method of measurement: blood biochemical tests.;Total cholestrol. Timepoint: before the intervention and 12 weeks after the intervention. Method of measurement: blood biochemical tests.;Triglyceride. Timepoint: before the intervention and 12 weeks after the intervention. Method of measurement: blood biochemical tests.;Low density lipoprotein. Timepoint: before the intervention and 12 weeks after the intervention. Method of measurement: blood biochemical tests.;High density lipoprotein. Timepoint: before the intervention and 12 weeks after the intervention. Method of measurement: blood biochemical tests.;Added at 2016-09-16: MDA. Timepoint: Added at 2016-09-16: before the intervention and 12 weeks after the intervention. Method of measurement: Added at 2016-09-16: blood biochemical tests.

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Secondary

Measure	Time frame
Blood pressure. Timepoint: before the intervention and 12 weeks after the intervention. Method of measurement: sphygmomanometer.;Weight. Timepoint: before the intervention and 12 weeks after the intervention. Method of measurement: digital scale.;BMI (Body Mass Index). Timepoint: before the intervention and 12 weeks after the intervention. Method of measurement: scale, meter.;Added at 2016-06-30: Total antioxidant capacity. Timepoint: Added at 2016-06-30: before the intervention and 12 weeks after the intervention. Method of measurement: Added at 2016-06-30: blood biochemical test.	—

Measure

Time frame

Blood pressure. Timepoint: before the intervention and 12 weeks after the intervention. Method of measurement: sphygmomanometer.;Weight. Timepoint: before the intervention and 12 weeks after the intervention. Method of measurement: digital scale.;BMI (Body Mass Index). Timepoint: before the intervention and 12 weeks after the intervention. Method of measurement: scale, meter.;Added at 2016-06-30: Total antioxidant capacity. Timepoint: Added at 2016-06-30: before the intervention and 12 weeks after the intervention. Method of measurement: Added at 2016-06-30: blood biochemical test.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactZeinab Yazdanpanah

Yazd Shahid Sadoughi University of Medical Sciences

yazd456@gmail.com+98 35 3524 8896

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026