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Determining concentration of Azithromycin in GCF after single dose adminstration

Determining concentration of Azitromycin in GCF after single dose administration in healthy subjects (by HPLC method)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201412033451N2
Enrollment
30
Registered
2014-12-23
Start date
2014-12-26
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Determine Concentration of Azithromycin in gingival crevicular fluid. Condition 2: Concentration of Azithromycin in gingival crevicular fluid. Dental examination Other special examinations and investigations of persons without complaint or reported diagnosis

Interventions

A group of 30 individuals were selected and a single dose of 250 mg Azithromycin were prescribed..
Treatment - Drugs
A group of 30 individuals were selected and a single dose of 250 mg Azithromycin were prescribed.

Sponsors

Dental Material Center , School of Dentistry , Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: The eligible and healthy volunteers will be enrolled in this case study only after receiving adequate information regarding purpose of the subject research and providing their consent for participation. Inclusion criteria: are having a gingival index less than 1.5 ; have adequate oral and general health conditions The exclusion criteria : are taking any oral medication in the last two weeks ; having an allergic reaction to Azithromycin ; gingivitis ; periodontitis ; showing any signs of gingival recession.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Concentration of Azithromycin in GCF. Timepoint: Ine the 0 . 6 . 12 36 . 84 . 156 hours azithromycin concentrations in GCF checked. Method of measurement: We used HPLC method for measuring Concentration of Azithromycin in GCF.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mahmood Khosravi Samani

Babol University of Medical Sciences

m.khosravi@mubabol.ac.ir+98 11 3219 9592

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026