ventilator associated pneumonia. Bacterial pneumonia, unspecified
Conditions
Interventions
Intervention 1: Patients in Selense group will receive bollus administraion of Selense (3000 µg) during 3 hours at the beginning, and then they will receive 1500 µg /day during one hour for 10 days. I
Treatment - Drugs
Placebo
Patients in Selense group will receive bollus administraion of Selense (3000 µg) during 3 hours at the beginning, and then they will receive 1500 µg /day during one hour for 10 days
Patients in control group will receive normal saline as the same volume and speed
Sponsors
Research deputy of Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion: ICU patients with positive SIRS and APACHE II score>15 and estimated to undergo mechanical ventilation for more than 48 hours Exclusion: age<18 years; pregnancy; history of CPR; malignancy; immunedepression; chronic renal failure and participating in another study
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ventilator Associated Pneumonia. Timepoint: days zero, 4th and 10th. Method of measurement: CPIS score. | — |
Secondary
| Measure | Time frame |
|---|---|
| ICU length of stay. Timepoint: duration of ICU stay. Method of measurement: days that patients was stayed in ICU. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSarvin Sanaie
Tabriz University of Medical Sciences
Outcome results
None listed