Spinal anesthesia.
Conditions
Interventions
Intervention 1: Meperidine 0.4 mg/kg, intravenously bolus immediately after intrathecal injection. Intervention 2: Ketamine 0.25 mg/kg plus midazolam 37.5 µg/kg, intravenously bolus immediately after
Prevention
Placebo
Meperidine 0.4 mg/kg, intravenously bolus immediately after intrathecal injection
Ketamine 0.25 mg/kg plus midazolam 37.5 µg/kg, intravenously bolus immediately after intrathecal injection
Meperidine 0.2 mg/kg plus dexamethasone 0.1 mg/kg, intravenously bolus immediately after intrathecal injection
Normal saline 5 cc, intravenously immediately after intrathecal injection as placebo
Sponsors
Shahid Beheshti Medical University
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:patients with elective orthopedic or urologic surgery aged between 20 and 60 years old. Exclusion criteria: Patients with cardiopulmonary disease; hypothyroidism or hperthyroidism; patients with psychologic disorders, a need for transfusion during surgery; an initial body temperature more than 38 or less than 36? C; a known history of alcohol or substance abuse; or receiving vasodilators; or medications likely to alter thermoregulation; patients with spinal anesthesia failure.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Shivering score. Timepoint: Thirty minutes after spinal anesthesia. Method of measurement: Observation based on Tsai scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Surface and core temperature. Timepoint: Every 15 minutes. Method of measurement: Based on centigrade,Ear termometer for core temperature and axillary termometer for surface temperature. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Solhpour
Shahid Beheshti University of Medical Sciences
Outcome results
None listed