ESRD patients on hemodialysis. Chronic kidney disease, stage 5
Conditions
Interventions
Intervention 1: In Children 500 Unit/kg/week subcutaneous injection after hemodialysis for 3 months. Intervention 2: Subcutaneous injection after dialysis 80 IU/kg/w for
3 months.
Treatment - Drugs
In Children 500 Unit/kg/week subcutaneous injection after hemodialysis for 3 months
Subcutaneous injection after dialysis 80 IU/kg/w for
3 months
Sponsors
Notarkib Biopharmaceutical Co.
Eligibility
Sex/Gender
All
Age
10 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: End Stage Renal Disease patients who were under hemodialysis and had a Glomerular filtration rate less than14 ml/min/1.73m2 together with a hematocrit less than30% or hemoglobin less than 10g/dl; Presence of Iron store(serum Ferritin) more than100mg/L and transferrin saturationmore than 20%);Patients aged between 10 to 60 years Exclusion Criteria:CRP more than 10mg/dl; uncontrolled hypertension; Symptomatic ischemic heart disease; History of cerebrovascular event; Graft rejection; Polycystic kidney disease ; Myeloma ; Malignancies
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemoglobin. Timepoint: Before using medicine and every 2 weeks till end of investigation. Method of measurement: Blood test.;Hematocrit. Timepoint: Before using the medicine and every 2 week till end of investigation. Method of measurement: Blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Younes Panahi
Baghiatalah Hospital
Outcome results
None listed