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The effect of intravenous adminastration of Aminophylline on prevention of post spinal Anesthesia Headache in patients undergoing elective cesarean Section

The effect of intravenous adminastration of Aminophylline on prevention of post spinal Anesthesia Headache in patients undergoing elective cesarean Section

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201411294923N6
Enrollment
140
Registered
2015-01-08
Start date
2014-07-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post spinal anesthesia headache. Other reaction to spinal and lumbar puncture

Interventions

Intervention 1: Prevention group: Intravenous injection of aminophylline 1 mg/kg in 100 cc normal salin. Intervention 2: Control group: injection of 100 cc normal salin.
Prevention
Prevention group: Intravenous injection of aminophylline 1 mg/kg in 100 cc normal salin
Control group: injection of 100 cc normal salin

Sponsors

Vice-chancellor Of Research Babol University Of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients candidate for spinal anesthesia set in class I & II of Anesthesia Society of America (ASA) was selected, Exclusion criteria: Patients with history of cardiovascular desease, cerebral, Hypertention,Diabet mellitus, Preeclampsia, Seizure, Migrain, History of Post spinal anesthesia headache, Unwilling to spinal anesthesia to experience spinal anesthesia, coagulopathy,Psychiatry.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Post spinal anesthesia headache. Timepoint: 4,8,24,48,72 hours after operation. Method of measurement: Score pain.

Secondary

MeasureTime frame
Blood pressure. Timepoint: Before and after spinal anesthesia and delivery and cord clamping and after drug injectionand then every 5 minutes until the end of operation. Method of measurement: Non- invasive manometer.;Heart rate. Timepoint: Before and after spinal anesthesia and delivery and cord clamping and after drug injectionand then every 5 minutes until the end of operation. Method of measurement: Heat rate monitoring.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Bahman Hasannasab

Babol University of Medical Sciences

bahmanh2002@yahoo.com+98 11 3223 8296

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026