Effects of Nitroglycerine on pain during Propofol injection

Comparison the pain control effects of Nitroglycerine versus placebo during the Propofol injection

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014112720112N1

Enrollment

100

Registered

2014-12-15

Start date

2012-02-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Open wound of leg. Open wound of lower leg, part unspecified

Interventions

Intervention 1: 200 microgram nitroglycerine diluted in 5 milliliter of saline. Intervention 2: 5 milliliter of saline.

Treatment - Drugs

Placebo

200 microgram nitroglycerine diluted in 5 milliliter of saline.

5 milliliter of saline.

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Participant inclusion criteria: American society of anesthesiologists class I and II patients; age between 18-70 years. exclusion criteria: thin dorsal hand veins; history of receiving analgesia or sedation within last 24 hours.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: every 30 Secondes. Method of measurement: Visual analogue scale.	—

Secondary

Measure	Time frame
Blood pressure. Timepoint: every 3 minutes. Method of measurement: sphygmomanometer.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPooya Derakhshan

Birjand University of Medical Sciences

pooyaderkh@yahoo.com+98 563222600

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026