Effect of transtracheal lidocaine and intravenous lidocaine on hemodynamic of Patients

Comparison the effect of transtracheal lidocaine and intravenous lidocaine on hemodynamic of Patients with hypertension undergoing drug treatment to tracheal intubation

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141127020112N10

Enrollment

Registered

2019-09-02

Start date

2017-03-21

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodynamic changes in patients with hypertension. Essential (primary) hypertension

Interventions

Intervention 1: Intervention group 1: In group A, fentanyl 2 mg/kg and intravenous lidocaine 2% 1.5mg/ kg was injected and anesthetized by thiopental 4 mg/kg and cisatracurium 0.2 mg/kg. Then, 30 seco

Eligibility

Sex/Gender

All

Age

40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with American Society of Anesthesiologists (ASA) grade 3 and lower

Exclusion criteria

Exclusion criteria: Emergency surgery Drug abuse Alcohol consumption All cases of difficult intubation Diabetes Heart failure Kidney failure Taking beta blocker Primary dysrhythmia Systolic pressure more than 170 mmHg Diastolic more than 100 mmHg

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: After 4 minutes, patients with appropriate endotracheal tube and 30 seconds after intubation were recorded, at 3, 6 and 9 minutes after intubation, blood pressure and heart rate. Method of measurement: Mercury barometer.;Heart rate. Timepoint: After 4 minutes, patients with appropriate endotracheal tube and 30 seconds after intubation were recorded, at 3, 6 and 9 minutes after intubation, blood pressure and heart rate. Method of measurement: Mercury barometer.	—

Measure

Time frame

Blood pressure. Timepoint: After 4 minutes, patients with appropriate endotracheal tube and 30 seconds after intubation were recorded, at 3, 6 and 9 minutes after intubation, blood pressure and heart rate. Method of measurement: Mercury barometer.;Heart rate. Timepoint: After 4 minutes, patients with appropriate endotracheal tube and 30 seconds after intubation were recorded, at 3, 6 and 9 minutes after intubation, blood pressure and heart rate. Method of measurement: Mercury barometer.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactPooya Derakhshan

Iran University of Medical Sciences

pooya_derakhshan@bums.ac.ir+98 21 6435 1444

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026