Effect of using extract of foeniculum vulgare with induction ovulation versus induction ovulation alone on pregnancy outcomes through invitro fertilization in infertile women with poor ovarian response

Effect of using extract of foeniculum vulgare with induction ovulation versus induction ovulation alone on pregnancy outcomes through invitro fertilization in infertile women with poor ovarian response: a before after clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201411269014N48

Enrollment

Registered

2014-12-02

Start date

2014-03-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility. Female infertility

Interventions

Intervention 1: drinking 200 ml extract of foeniculum vulgare daily for 2 months and then induction ovulation. Intervention 2: induction ovulation alone.

Treatment - Drugs

drinking 200 ml extract of foeniculum vulgare daily for 2 months and then induction ovulation

induction ovulation alone

Eligibility

Sex/Gender

Female

Age

35 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: (a) infertility with poor ovarian response; (b) age of 35 years; (c) FHS equal to or greater than 10 mIU/ml on the third day of menstrual period; (d) ovarian volume equal to or greater than 3 ml; (e) history of unsuccessful IVF; (f) number of ovules less than 3 to 5. Exclusion criteria: (a) FSH more than 20 mIU/ml on the second to fourth days of menstrual period; (b) women with uterine anomaly or obstruction of uterine tube; (c) using corticosteroid during the last 5 months; (d) contraindication of pregnancy; (e) missing of one ovary; (f) systemic diseases such as diabetes, adrenal dysfunction, hypothalamus tumor, hyperprolactinemia, and intracranial damages.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Number of follicles. Timepoint: before and 2 months after intervention. Method of measurement: using ultrasonography.;Number of ovule. Timepoint: before and 2 months after intervention. Method of measurement: using microscope.;Number of fetus. Timepoint: before and 2 months after intervention. Method of measurement: using microscope.;Number of pregnancy. Timepoint: before and 2 months after intervention. Method of measurement: using ultrasonography.	—

Measure

Time frame

Number of follicles. Timepoint: before and 2 months after intervention. Method of measurement: using ultrasonography.;Number of ovule. Timepoint: before and 2 months after intervention. Method of measurement: using microscope.;Number of fetus. Timepoint: before and 2 months after intervention. Method of measurement: using microscope.;Number of pregnancy. Timepoint: before and 2 months after intervention. Method of measurement: using ultrasonography.

—

Secondary

Measure	Time frame
Number of receiving HMG. Timepoint: before and 2 months after intervention. Method of measurement: through checking medical record.;Number of induction. Timepoint: before and 2 months after intervention. Method of measurement: through checking medical record.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Elnaz Mohammadai

Fatemieh Hospital

el.mohamadi@umsha.ac.ir+98 81 8287 7459

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026