Minor aphthous. Aphthous stomatitis (major)(minor)
Conditions
Interventions
Intervention 1: Administration of a mouthwash from decoction of leaves of tabacco which must be gargled as 10 ml of mouthwash 3 times a day. Intervention 2: Placebo is prepared in similar container in
Treatment - Drugs
Placebo
Administration of a mouthwash from decoction of leaves of tabacco which must be gargled as 10 ml of mouthwash 3 times a day.
Placebo is prepared in similar container including distilled water with approved color additives which looked the same as the tobacco mouthwash and must be gargled as 10 ml of mouthwash 3 times a day.
Sponsors
Siavash Vaziri
Eligibility
Sex/Gender
All
Age
15 Years to 65 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria are as follows: men and women aged 15–65 years old; willingness to participate and sign the informed agreement forms; patients with 1 to 5 aphthous ulcers (less than 48 hours’ duration); an anticipation that their ulcers normally take 5 or more days to resolve without treatment; ulcers must be in positions simply accessible for evaluation and treatment; patients with normal sense of pain and exclusion criteria are the following: a known history of severe drug hypersensitivities; pregnancy or lactation; ulcers as a manifestation of a systemic disease process, including Behçet disease, serious anemia Crohn’s disease, ulcerative colitis, or acquired immune deficiency syndrome; simultaneous clinical conditions which represent a health risk to the subjects, such as severe heart, liver, or kidney disorder; treatment with NSAIDs drugs, systemic steroids or other immunomodulatory agents.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ulcer size. Timepoint: 5 days. Method of measurement: Millimeter.;Pain level. Timepoint: 5 days. Method of measurement: Visual analog scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSiavash Vaziri
Department of Infectious Disease, Imam Reza Hospital
Outcome results
None listed