The efficacy of Dorema ammoniacum D. Don oleo-gum-resin on chloasma

Formulationand evaluation of the efficacy of topicalpreparation from Dorema ammoniacum D. Don oleo-gum-resin in patients with chloasma

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141124020071N4

Enrollment

Registered

2019-01-26

Start date

2018-10-06

Completion date

Unknown

Last updated

2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chloasma. Chloasma

Interventions

Intervention 1: Intervention group: use of 1 grams topicalpreparation from Dorema ammoniacum D. Don oleo-gum-resin twice daily for 1 month. Intervention 2: Control group: use of 1 grams Eucerine Cre

Eligibility

Sex/Gender

All

Age

14 Years to 66 Years

Inclusion criteria

Inclusion criteria: Being at the age of 14_66 years old Men and women The patients have mild to moderate melasma according to melasma severity index (MSI)

Exclusion criteria

Exclusion criteria: The patients have used the bleaching materials within 2 weeks before intervention Pregnancy test for female participants is positive

Design outcomes

Primary

Measure	Time frame
Chloasma. Timepoint: Before using the drug _ 30 days after the drug. Method of measurement: Based on Dermatology QOL (quality of life) Question and MSI (melasma severity index).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Hosein Farzaei

Kermanshah University of Medical Sciences

mh-farzaee@razi.tums.ac.ir+98 83 3825 0271

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026