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Comparing adding diltiazem to tolterodine to treat overactive bladder after prostatectomy

Comparing adding and not adding diltiazem to tolterodine to treat overactive bladder after prostatectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014112214333N25
Enrollment
80
Registered
2015-01-08
Start date
2014-02-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overactive bladder syndrome. other specified disorders of bladder

Interventions

Intervention 1: The control group received 2 mg tolterodine (regular treatment) and 60 mg placebo twice a day. Then, their blood pressure was measured using a pressure set and symptoms of urinary syst
Treatment - Drugs
The control group received 2 mg tolterodine (regular treatment) and 60 mg placebo twice a day. Then, their blood pressure was measured using a pressure set and symptoms of urinary system were checked
The experiment group received 2 mg tolterodine and 60 mg diltiazem (the regular treatment) twice a day. Then, their blood pressure was measured using a pressure set and symptoms of urinary system were

Sponsors

Vice Chancellor for Research Affairs, Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
55 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion: male patients ranging from 55 to 80, patients with prostatectomy; patients in urology department, patients with blood pressure background. Exclusion: patients with heart failure, bradycardia, having background of radiation to bladder, BCG therapy, systolic pressure less than 120 mm Hg, dependency of patient to medicine.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Blood pressure. Timepoint: A day before and four weeks after surgery. Method of measurement: With a pressure set.;Urinary system. Timepoint: A day before and four weeks after surgery. Method of measurement: Based on IPSS.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026