pain after laparascopic cholecystectomy. calculus of gallbladder without cholecystitis
Conditions
Interventions
Intervention 1: The night before surgery, 1200mg oral N-acethylcysteine in the form of two effervescent tablets (600mg)dissolved in water were given to the intervention group and the morning before o
Treatment - Drugs
The night before surgery, 1200mg oral N-acethylcysteine in the form of two effervescent tablets (600mg)dissolved in water were given to the intervention group and the morning before operation, 3cc of
For the control group, two vit c effervescent tablets (placebo) dissolved in water, were given at night before surgery and 3cc distilled water in 100cc normal saline as placebo transfused in 5 minutes
Sponsors
Vice chancellor for research, Babol University of Medical Science
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 20-50 years old; candidate for laparascopic cholecystectomy; ASA class1(healthy patient without other disease). Exclusion criteria: previous abdominal surgery; known sensitivity to N- acethylcystein; operation time more than 2 hours; any uncommon complication in operation or in intubation; chronic pain before operation; neuropsychiatric disease; addiction; pregnancy; lactation and other concurrent surgery.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: in recovery and 1, 2, 4, 8, 12 and 24 hours after operation. Method of measurement: visual analog scale(VAS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Nausea and vomiting. Timepoint: In recovery and 1, 2, 4, 8, 12 and 24 hour after operation. Method of measurement: scale 0-4. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMrs Sedighe Soleimanian
Babol Universityof Medical Science
Outcome results
None listed