The effect of lidocaine and cold normal saline on injection pain

Comparison of the effect of lidocaine and cold normal saline on pain during propofol injection

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141121020020N7

Enrollment

120

Registered

2021-06-08

Start date

2021-03-13

Completion date

Unknown

Last updated

2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain at the injection site.

Interventions

Intervention 1: Intervention group: Lidocaine receiving group. Patients in this group receive 10 ml of 0.5% lidocaine as an intervention group. Intervention 2: Intervention group: Recipient of normal

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Indication of propofol injection Elective general anesthesia

Exclusion criteria

Exclusion criteria: Known heart disease History of lidocaine sensitivity Patient dissatisfaction History of seizures History of psychiatric illness

Design outcomes

Primary

Measure	Time frame
Pain severity at the injection site. Timepoint: At beginning, at 15 and 30 seconds after injection. Method of measurement: Questionnaire and VAS scoring scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahram Seyfi

Babol University of Medical Sciences

sh.seyfi@mubabol.ac.ir+98 11 3223 8301

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026