A comparison between intravenous and topical spray of lidocaine on discomfort feeling in throat/larynge in general anesthesia

A comparison between intravenous and topical spray of lidocaine on hemodynamic changes and discomfort feeling in throat/larynge following to LMA insertion in general anesthesia

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141121020020N5

Enrollment

120

Registered

2020-06-06

Start date

2020-02-18

Completion date

Unknown

Last updated

2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General Anesthesia. Other complications of anesthesia

Interventions

Intervention 1: Intervention group: Three minutes before LMA placement, 1.5 mg / kg intravenous lidocaine (Aborihan Comany) and normal saline (Samen Company) spray are given at the bottom of the throa

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 18-65 years old ASA class I-II

Exclusion criteria

Exclusion criteria: History of laryngeal or tracheal surgery, History of allergic reaction Smoking Addiction

Design outcomes

Primary

Measure	Time frame
Blood Pressure. Timepoint: Before and during intervention and after recovery time. 1, 3, 5, 10, 15 min after drug injection and 3, 5, 15, 30 min after recovery. Method of measurement: Blood pressure manometer by mmHg.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahram Seyfi

Babol University of Medical Sciences

ficu_ss@yahoo.com009811322335308

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026