Effect of Granisetron in prevention of shivering after spinal anesthesia in lower Abdominal Surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201411203915N14

Enrollment

105

Registered

2014-12-09

Start date

2014-03-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Shivering after regional anesthesia. Complications of medical and surgical care

Interventions

Intervention 1: Group A : Administration of intavenous granisetrone 1mg before spinal anesthesia. Intervention 2: Group B: Administration of intravenous granisetrone 3 mg befor spinal anesthesia. Inte

Treatment - Drugs

Group A : Administration of intavenous granisetrone 1mg before spinal anesthesia

Group B: Administration of intravenous granisetrone 3 mg befor spinal anesthesia

group C: Administration of intravenous saline normal 5 ml before spinal anesthesia

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: ages 18-60 yr; American society of anesthesia (ASA) class 1-2; elective inguinal hernia repair with spinal anesthesia. Exclusion criteria: patients refuse of spinal anesthesia; any contraindication for regional anesthesia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Post-operative shivering. Timepoint: Till 2 hours after surgery. Method of measurement: Clinical assessment.	—

Secondary

Measure	Time frame
Need for petidine administration. Timepoint: Till 2 hours after surgery. Method of measurement: Clinical assessment.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Ali Peirovifar

Tabriz University of Medical Sciences

peirovifara@gmail.com+98 41 3334 7054

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026