Respiratory Distress Syndrome. Respiratory distress syndrome
Conditions
Interventions
Intervention 1: Intervention group: administration of surfactant 4cc/kg survanta in 4 divided dose via laryngeal mask after receiving 1-2 µ/kg intravenous fentanyl. Intervention 2: Control group: admi
Treatment - Drugs
Intervention group: administration of surfactant 4cc/kg survanta in 4 divided dose via laryngeal mask after receiving 1-2 µ/kg intravenous fentanyl
Control group: administration of surfactant 4cc/kg survanta in 4 divided dose via endotracheal tube after receiving 1-2 µ/kg intravenous fentanyl
Sponsors
Research Vice Chancellor for Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Days to 3 Days
Inclusion criteria
Inclusion criteria: Inclusion criteria: gestation age 33-37 weeks; confirmed diagnosis of respiratory distress syndrome according to clinical and radiological findings; treatment with surfactant Exclusion criteria: major congenital anomalies; congenital heart disease; cranio-facial anomalies; esophageal atresia; birth weight less than 1800 grams
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduced needed FiO2 to maintain adequate oxygenation. Timepoint: Before and one hour after surfactant therapy. Method of measurement: Determination of needed Fio2 in blender and by pulse oxymetry. | — |
Secondary
| Measure | Time frame |
|---|---|
| Need for intubation and assisted ventilation. Timepoint: Till 3 days after treatment. Method of measurement: Pulse oxymetry and blood gas analysis. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Reza Radfar
Al Zahra Hospital
Outcome results
None listed