Effect of increasing the amount of milk protein content by protein supplement on growth indices of preterm infants

Evaluating the effect of increasing the amount of milk protein content by protein supplement on growth indices of preterm infants

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141118019991N3

Enrollment

Registered

2021-09-16

Start date

2014-03-20

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Very Low Birth Weight. Extremely low birth weight newborn, unspecified weight

Interventions

Intervention 1: Intervention group: High protein diet (4 grams per kilogram per day) which is provided by protein supplement, when the enteral feeding has been started. Intervention 2: Control group:

Eligibility

Sex/Gender

All

Age

1 Days to 30 Days

Inclusion criteria

Inclusion criteria: Gestational age less than 34 weeks Birth weight less than 1500 grams No anomalies which affect on growth

Exclusion criteria

Exclusion criteria: Parents disapproval Unable to continue feeding more than 72 hours Urea over than 50 milligram per deciliter

Design outcomes

Primary

Measure	Time frame
Weight. Timepoint: Daily from the first day of life. Method of measurement: Digital scale.;Height. Timepoint: Weekly from the first day of life. Method of measurement: meter.;Head Circumference. Timepoint: Weekly from the first day of life. Method of measurement: meter.	—

Secondary

Measure	Time frame
Urea. Timepoint: Biweekly. Method of measurement: Blood Sample Enzymatic tests (gr/dl).;?Bicarbonate. Timepoint: Biweekly. Method of measurement: Blood Sample enzymatic auto-analyzer.;Calcium. Timepoint: Biweekly. Method of measurement: Blood Sample Enzymatic tests (mg/dl).;Phosphorus. Timepoint: Biweekly. Method of measurement: Blood Sample Enzymatic tests (mg/dl).;Alkaline phosphatase. Timepoint: Biweekly. Method of measurement: Blood Sample Enzymatic tests.;Albumin. Timepoint: Biweekly. Method of measurement: Blood Sample Enzymatic tests.;Total protein. Timepoint: Biweekly. Method of measurement: Blood Sample Enzymatic tests (gr/dl).;Clinical and Para-clinical sign of Necrotizing Enterocolitis. Timepoint: Multiple clinical Evaluation per day, and if needed also Para-clinical evaluation. Method of measurement: Clinical and Para-clinical Signs and symptoms.;Sepsis Early or Late Onset, clinical or Para-clinical Sign and Symptoms. Timepoint: Multiple clinical Evaluation per day, and if needed also Para-clinical evaluation. Method of measurement: Clinical and Para-clinical Signs and Symptoms.;Hospitalization Duration. Timepoint: Hospitalization Duration by days number at discharge. Method of measurement: Hospitalization Duration days.	—

Measure

Time frame

Urea. Timepoint: Biweekly. Method of measurement: Blood Sample Enzymatic tests (gr/dl).;?Bicarbonate. Timepoint: Biweekly. Method of measurement: Blood Sample enzymatic auto-analyzer.;Calcium. Timepoint: Biweekly. Method of measurement: Blood Sample Enzymatic tests (mg/dl).;Phosphorus. Timepoint: Biweekly. Method of measurement: Blood Sample Enzymatic tests (mg/dl).;Alkaline phosphatase. Timepoint: Biweekly. Method of measurement: Blood Sample Enzymatic tests.;Albumin. Timepoint: Biweekly. Method of measurement: Blood Sample Enzymatic tests.;Total protein. Timepoint: Biweekly. Method of measurement: Blood Sample Enzymatic tests (gr/dl).;Clinical and Para-clinical sign of Necrotizing Enterocolitis. Timepoint: Multiple clinical Evaluation per day, and if needed also Para-clinical evaluation. Method of measurement: Clinical and Para-clinical Signs and symptoms.;Sepsis Early or Late Onset, clinical or Para-clinical Sign and Symptoms. Timepoint: Multiple clinical Evaluation per day, and if needed also Para-clinical evaluation. Method of measurement: Clinical and Para-clinical Signs and Symptoms.;Hospitalization Duration. Timepoint: Hospitalization Duration by days number at discharge. Method of measurement: Hospitalization Duration days.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaharnaz Talebiyan

Tehran University of Medical Sciences

s_talebiyan@yahoo.com+98 21 2274 9212

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026