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Study the effect of vitamin C on saliva antioxidant defense system of patients with periodontal disease

Effect of using and avoiding to use vitamin C on defense system of saliva anti oxidant of periodontal patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014111714333N24
Enrollment
32
Registered
2014-12-23
Start date
2014-12-06
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disease of salivary gland, unspecified. Disease of salivary gland, unspecified

Interventions

Intervention 1: Samples of experimental group received 500 mg of oral vitamin C power daily for three weeks. Unstimulated saliva of patients was tested in the morning and patients were asked to brush
Treatment - Drugs
Placebo
Samples of experimental group received 500 mg of oral vitamin C power daily for three weeks. Unstimulated saliva of patients was tested in the morning and patients were asked to brush their teeth and
Samples of control group received 500 mg of water with permissible oral essence and color for three weeks. Unstimulated saliva of patients was first gathereded in the morning and patients were asked

Sponsors

Vice Chancellor for Research Affairs, Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion: written satisfaction by 20 patients; having at least teeth; propping depth deeper than 5 mm and clinical attachment level less than 3 mm at least 30 % of sites; bleeding while propping; chronic gum inflammation; systematically healthy patients; patient who had not received propping treatment during last 6 months. Exclusion: patients using antibiotics or anti inflammatory medicine; having systematic disease history; pregnant and breast feeding women; those who use vitamin supplements; those who use mouthwash; those who smoke.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Saliva anti oxidant. Timepoint: At the beginning of study and three weeks after that. Method of measurement: Using Randox kit.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026