Headache. Headache
Conditions
Interventions
Intervention 1: ketorolac 30 mg IV + o2 15 lit/min with non rebreathing mask. Intervention 2: ketorolac 30 mg IV +o2 7 lit/min with 60% venturi mask. Intervention 3: ketorolac 30 mg IV+ o2 4 lit/min n
Treatment - Drugs
Placebo
ketorolac 30 mg IV + o2 15 lit/min with non rebreathing mask.
ketorolac 30 mg IV +o2 7 lit/min with 60% venturi mask
ketorolac 30 mg IV+ o2 4 lit/min nasal
ketorolac 30 mg IV + Room air
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: inclusion criteria: age 18 years and above; moderate and severe primary recurrent headaches. exclusion criteria: suspicious to secondary headaches based on the attending physician's judgment; abnormal vital signs; variation in the level of consciousness;fever; focal neurologic finding;allergy to NSAIDs; History of peptic ulcer diseases or gastrointestinal bleeding; pregnancy; mild pain( Vas score: 3 or less).
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score. Timepoint: 0,15,30,45,60 min. Method of measurement: Visual analog scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| ED length of stay, morphine dosage, recurrencerate. Timepoint: 24 hour. Method of measurement: medical document. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactEhsan Karimi
Tehran University of Medical Sciences
Outcome results
None listed