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Atorvastatin in acute intracerebral hemorrhage.

The effect of Atorvastatin on the blood-brain barrier biomarkers in acute intracerebral hemorrhage, a pilot clinical trial.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141116019971N6
Enrollment
92
Registered
2022-06-26
Start date
2022-07-23
Completion date
Unknown
Last updated
2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intracerebral Hemorrhage. Nontraumatic intracerebral hemorrhage in hemisphere, unspecified

Interventions

Intervention 1: Intervention group:Tab Atorvastatin 40 mg per day will be administered for 45 days. In addition, routine medical treatment including antihypertensive drugs will be given to the patien

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 80 Years

Inclusion criteria

Inclusion criteria: Age 40 mg/dL.

Exclusion criteria

Exclusion criteria: Pregnancy. Coma at the time of admission. History of neurodegenerative disorders such as Alzheimer's disease, Multiple sclerosis, Parkinson's disease, previous stroke, and psychological problems. History of brain tumors. Intracerebral hemorrhage due to vascular malformation or coagulation disorders. Intracerebral hemorrhage which requires surgical evacuation.

Design outcomes

Primary

MeasureTime frame
Serum level of Matrix metallopeptidase 9. Timepoint: At the time of admission (before intervention) and after 14 and 45 days of Atorvastatin consumption. Method of measurement: Blood Sample.;Serum level of Vascular endothelial growth factor. Timepoint: At the time of admission (before intervention) and after 14 and 45 days of Atorvastatin consumption. Method of measurement: Blood Sample.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEhsan Karimialavijeh

Tehran University of Medical Sciences

drkarimi86@gmail.com+98 21 6634 8500

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026