Cerebral infarction. Sequelae of cerebral infarction
Conditions
Interventions
Intervention 1: Group A: participants were received capsules containing 20 mg of Fluxetine orally, daily for 90 days, as well as physiotherapy sessions 1 hour per day, 5 days per week, for 12 weeks. I
Treatment - Drugs
Group A: participants were received capsules containing 20 mg of Fluxetine orally, daily for 90 days, as well as physiotherapy sessions 1 hour per day, 5 days per week, for 12 weeks.
Group B: participants were received capsules containing 20 mg of Citaloprem orally, daily for 90 days, as well as physiotherapy sessions 1 hour per day, 5 days per week, for 12 weeks.
Control group: participants were received capsules containing microcrystalline cellulose, orally, daily for 90 days, as well as physiotherapy sessions 1 hour per day, 5 days per week, for 12 weeks.
Sponsors
Vice chancellor for research, Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Over 18 years of age Suffering from hemiparesis or hemiplegia as a result of a first-time acute (in the past 24 hours) ischemic stroke An initial Fugl-Meyer Motor Scale score of under 55
Exclusion criteria
Exclusion criteria: A National Institutes of Health Stroke Scale score of less than five Prior disabilities including aphasia, cognitive disorders and motor disorders due to stroke or any other neurodegenerative disease Pregnancy or breastfeeding Currently taking antidepressants Contraindications of therapy, including renal insufficiency (glomerular filtration rate <30 ml/min), abnormal liver function tests, hyponatremia and a long QT interval on an electrocardiogram and Any significant adverse effects (agitation, hypertension or other signs of serotonin syndrome) after initiation of treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Motor function. Timepoint: At recruitment and after 90 days. Method of measurement: Fugl-Meyer Motor Scale score. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactEhsan Karimialavijeh
Tehran University of Medical Sciences
Outcome results
None listed