Effect of Taroneh on treatment of male infertillity

Evaluate of effectiveness of Taroneh (traditional medicine product) on sperm parameters of infertile men and comparison with the drug pentoxifylline

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014111519965N1

Enrollment

Registered

2016-02-19

Start date

2015-10-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

male infertility. Male infertility

Interventions

Intervention 1: Intervention Group: 3 gram powder of Taroneh in sachet, twice a day for 90 day Taroneh will purchase from south groves of Iran. Intervention 2: Control Group: one tablet of Pentoxify

Treatment - Drugs

Intervention Group: 3 gram powder of Taroneh in sachet, twice a day for 90 day Taroneh will purchase from south groves of Iran

Control Group: one tablet of Pentoxifyilline (400mg) (Farabi pharmaceutical company) daily for 90 days

Eligibility

Sex/Gender

Male

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Idiopathic oligospermia; Idiopathic Asthenospermia; Idiopathic Teratospermia; Idiopathic Oligoasthenospermia; Idiopathic Oligoteratospermia; Idiopathic Oligoteratoasthenospermia; 18-35 Age; Patient’s wife age 18-35; Absence of azoospermia; Non-consuming use of other drug for treatment of infertility during the study Exclusion criteria: lack of patient cooperation; the incidence of serious side effects, Age more than 35, Age of patient’s spouse more than 35

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Sperm count concentration. Timepoint: Before intervention and then four months after the start of intervention (one month after the end of intervention). Method of measurement: Semen analysis.;Total sperm count. Timepoint: Before intervention and then four months after the start of intervention (one month after the end of intervention). Method of measurement: Semen analysis.;Motility. Timepoint: Before intervention and then four months after the start of intervention (one month after the end of intervention). Method of measurement: Semen analysis.;Morphology. Timepoint: Before intervention and then four months after the start of intervention (one month after the end of intervention). Method of measurement: Semen analysis.	—

Measure

Time frame

Sperm count concentration. Timepoint: Before intervention and then four months after the start of intervention (one month after the end of intervention). Method of measurement: Semen analysis.;Total sperm count. Timepoint: Before intervention and then four months after the start of intervention (one month after the end of intervention). Method of measurement: Semen analysis.;Motility. Timepoint: Before intervention and then four months after the start of intervention (one month after the end of intervention). Method of measurement: Semen analysis.;Morphology. Timepoint: Before intervention and then four months after the start of intervention (one month after the end of intervention). Method of measurement: Semen analysis.

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Secondary

Measure	Time frame
Upper respiratory tract's reaction to Taroneh. Timepoint: When the incidence of adverse drug reactions in patient. Method of measurement: According CTC (Common Toxicity Criteria).;Volume. Timepoint: Before intervention and then four months after the start of intervention (one month after the end of intervention). Method of measurement: Semen analysis.;Viscosity. Timepoint: Before intervention and then four months after the start of intervention (one month after the end of intervention). Method of measurement: Semen analysis.	—

Measure

Time frame

Upper respiratory tract's reaction to Taroneh. Timepoint: When the incidence of adverse drug reactions in patient. Method of measurement: According CTC (Common Toxicity Criteria).;Volume. Timepoint: Before intervention and then four months after the start of intervention (one month after the end of intervention). Method of measurement: Semen analysis.;Viscosity. Timepoint: Before intervention and then four months after the start of intervention (one month after the end of intervention). Method of measurement: Semen analysis.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadreza Mirzaei

Tehran University of Medical Sciences

mirzaei-m@razi.tums.ac.ir+98 21 5563 9724

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026