Diabetes mellitus. Non-insulin-dependent diabetes mellitus
Conditions
Interventions
Intervention 1: Resveratrol- 240 mg/day for 8 week. Intervention 2: Placebo-240mg/day for 8 week.
Treatment - Other
Placebo
Resveratrol- 240 mg/day for 8 week
Placebo-240mg/day for 8 week
Sponsors
Vice chancellor for research, Iran University of Medical Science
Eligibility
Sex/Gender
All
Age
45 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: diagnosis of type 2 Diabetes for at least 2 years; willing to participate; a minimum score of 10 in Beck Depression Inventory; age between 45 to 70 years old. Exclusion criteria: Significant diseases including cardiovascular, renal and liver diseases, or cancer; pregnancy; lactation; consumption of antidepressant agents within the past 8 weeks; insulin use; consumption of nutritional supplements within the past 8 weeks.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mood. Timepoint: At baseline and after weeks 4 and 8. Method of measurement: Beck Depression Inventory.;Cognitive performance. Timepoint: At baseline and after weeks 4 and 8. Method of measurement: Questionnaire.;Serum BDNF(brain-derived neurotrophic factor ). Timepoint: At baseline and after 8 weeks. Method of measurement: ELISA. | — |
Secondary
| Measure | Time frame |
|---|---|
| HbA1c. Timepoint: At baseline and after 8 weeks. Method of measurement: Biochemical Assessment.;Fasting Blood Sugar. Timepoint: At the begining and end(week 8) of intervention. Method of measurement: Biochemical measurements. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFahime Ahmadi Motlaq
Department of Nutrition, School of Public Health, Iran University of Medical Sciences.
Outcome results
None listed