Comparison of the Effect of Lidocaine-Morphine and Lidocaine-Ketamine Spray on Post-Tonsillectomy Pain

Comparison of the Effect of Lidocaine-Morphine and Lidocaine-Ketamine Spray on Post-Tonsillectomy Pain in Children

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014111019037N4

Enrollment

120

Registered

2014-11-17

Start date

2013-10-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain in throat (surgery site). Pain in throat

Interventions

Intervention 1: First intervention group: Local usage of handmade Lidocaine-Morphine spray (including Lidocaine 10% spray from Irandarou manufacturing company, Tehran, Iran, registered No. 1228129223

Treatment - Drugs

First intervention group: Local usage of handmade Lidocaine-Morphine spray (including Lidocaine 10% spray from Irandarou manufacturing company, Tehran, Iran, registered No. 1228129223 and Morphine 1

Second intervention group: Local usage of handmade Lidocaine-Ketamine spray (including Lidocaine 10% spray from Irandarou manufacturing company, Tehran, Iran, registered No. 1228129223 and Ketamine

Third intervention group: Local usage of handmade normal saline spray (including normal saline solution 9mg/ml from Daroupakhsh drug manufacturing company, Tehran, Iran, registered No. 1228057458): 1

Eligibility

Sex/Gender

All

Age

6 Years to 12 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 6 to 12 years old children who are candidate for elective tonsillectomy. Exclusion criteria: Patients who usually use anticonvulsants or analgesics or anti-inflammatory agents; patients with history of allergy to morphine or lidocaine; patients with underline diseases like asthma.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Post-operation pain. Timepoint: From the enterance to the recovery ward until one hour (every 20 minutes). Method of measurement: Questionnaire.	—

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026