melasma. Chloasma
Conditions
Interventions
Intervention 1: Intervention group 2: Hydroquinone 4%, will be used once a day for 4 months.
Manufacturing by Behvazan Pharmaceutical Company. Intervention 2: Intervention group 1: Azelaic acid 20%,
Treatment - Drugs
Intervention group 2: Hydroquinone 4%, will be used once a day for 4 months.
Manufacturing by Behvazan Pharmaceutical Company.
Intervention group 1: Azelaic acid 20%, to be applied once a day for 4 months.
Manufacturing by Sepidaj Pharmaceutical Companies.
Sponsors
Vice Chancellor for Researc?h, Hamadan university of medical science
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: melasma patients with a clinical diagnosis. Exclusion criteria: Patients who are pregnant or breastfeeding; Patients who are treated with anticonvulsant and corticosteroid drugs; Patients who are treated with OCP; Out Worker's patients; Patients who have a history of sensitivity to AZ or HQ; Patients with underlying systemic disease (hypothyroidism and liver function Diss) are; Patients who have used a local drug during the previous month.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MASI score. Timepoint: 0, 1, 2 and 4 months. Method of measurement: checklist. | — |
Secondary
| Measure | Time frame |
|---|---|
| -. Timepoint: -. Method of measurement: -. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Mozhgan Bahadori
Department of Dermatology University of Medical Sciences
Outcome results
None listed