Migraine without aura [common migraine]. Migraine without aura [common migraine]
Conditions
Interventions
Intervention 1: Intervention: 2 ml of chamomile oil oleogel is applied topically on forehead, temporal and behind ears when headache is started. It will be done two times of migraine attack. Intervent
Treatment - Drugs
Placebo
Intervention: 2 ml of chamomile oil oleogel is applied topically on forehead, temporal and behind ears when headache is started. It will be done two times of migraine attack.
2 ml of placebo oleogel is applied topically on forehead, temporal and behind ears when headache is started. It will be done two times of migraine attack.
Sponsors
Vice Chancellor for research of Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: All patients between 18 and 65 years; having a definite diagnosis of migraine headache according to the standards of the International Headache Society (IHS 1.1); at least a 1 year history of migraine; first attack started under the age of 50 years; with 1–6 migraine attacks per month Exclusion criteria: Patients who had a history of eczema and any kind of hypersensitivity reaction; any skin lesion in the temporal and forehead areas of the head; severe headache which does not respond to at least three types of abortive behind the counter medications; headache lasting more than 15 days per month for 3 months or more; a history of any neurological disorder except migraine; receiving any medication for prophylaxis of migraine from 1 month before the beginning of the study; pregnancy; breast feeding; inability to read comprehend and complete diary forms
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Migraine headache amount. Timepoint: two attacks (drug) Two attacks (Placebo). Method of measurement: Visual Analogue Scale (VAS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Nausa. Timepoint: 24 hours after using each drug. Method of measurement: Visual Analogue Scale (VAS).;Vomiting. Timepoint: 24 hours after using each drug. Method of measurement: Visual Analogue Scale (VAS).;Photophobia. Timepoint: 24 hours after using each drug. Method of measurement: Visual Analogue Scale (VAS).;Phonophobia. Timepoint: 24 hours after using each drug. Method of measurement: Visual Analogue Scale (VAS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Arman Zargaran
Shiraz University of Medical Sciences
Outcome results
None listed