Effect of garlic on patients with Non-Alcoholic Fatty Liver Disease

Effect of garlic on liver function, sonographic findings and body composition in patients with Non-Alcoholic Fatty Liver Disease

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014110819853N1

Enrollment

100

Registered

2014-12-18

Start date

2014-11-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non-alcoholic fatty liver disease. Fatty (change of) liver, not elsewhere classified

Interventions

Intervention 1: Intervention group: Garlic Tab 400 mg 2 times in day for 15 weeks (each tablet contains 1500 microgram allicin). Intervention 2: Control groups: tablet of starch? 2 times per day for 1

Treatment - Drugs

Placebo

Intervention group: Garlic Tab 400 mg 2 times in day for 15 weeks (each tablet contains 1500 microgram allicin)

Control groups: tablet of starch? 2 times per day for 15 weeks

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria :60> age >20;serum level of alanin aminotranspherase and aspartat aminotranspherase more than 40; fatty liver on ultra sound. exclusion criteria : pregnancy; breast feeding; alcohol; other liver diseases; diet or treatment for fatty liver in 3 month past; autoimmune diseases and cancers.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
ALT. Timepoint: before and 15 weeks after intervention. Method of measurement: photometric.;AST. Timepoint: before and 15 weeks after intervention. Method of measurement: photometric.;The severity of fatty liver. Timepoint: before and 15 weeks after intervention. Method of measurement: ultrasound.	—

Secondary

Measure	Time frame
Body composition. Timepoint: befor and 3 month of intervention. Method of measurement: instrument body composition.;FBS. Timepoint: befor and 3 month of intervention. Method of measurement: photometric.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPaknahad

Isfahan University of Medical Sciences

paknahad@hlth.mui.ac.ir+98 31 3792 2784

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026