The effects of garlic tablet in patients with rheumatoid arthritis.

The effects of garlic tablet on inflammatory biomarkers, serum total antioxidant capacity, serum malondialdehyde, fatigue, and clinical symptoms in patients with rheumatoid arthritis.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141108019853N6

Enrollment

Registered

2019-10-01

Start date

2019-10-02

Completion date

Unknown

Last updated

2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rheumatoid arthritis. Rheumatoid arthritis disease

Interventions

Intervention 1: Intervention group: Patients in the intervention group receive 500 mg garlic tablets twice a day for 8 weeks. Intervention 2: Control group: control group receive placebo.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Diagnosis of rheumatoid arthritis by a physician based on criteria (ACR) Having active disease Intake of stable doses of corticosteroids during the past month.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Mean difference of serum CRP. Timepoint: Before and after intervention. Method of measurement: Serum level.;Mean difference of serum TNFa . Timepoint: Before and after intervention. Method of measurement: Serum level.;Mean difference of serum TAC. Timepoint: Before and after intervention. Method of measurement: Serum level.;Mean difference of serum MDA . Timepoint: Before and after intervention. Method of measurement: Serum level.;Mean difference of ESR. Timepoint: Before and after intervention. Method of measurement: Photo-metric.;Mean difference fatigue score in fatigue questionnaire. Timepoint: Before and after intervention. Method of measurement: Fatigue questionnaire.;Mean difference of clinical symptoms. Timepoint: Before and after intervention. Method of measurement: DAS-28 questionnaire.	—

Measure

Time frame

Mean difference of serum CRP. Timepoint: Before and after intervention. Method of measurement: Serum level.;Mean difference of serum TNFa . Timepoint: Before and after intervention. Method of measurement: Serum level.;Mean difference of serum TAC. Timepoint: Before and after intervention. Method of measurement: Serum level.;Mean difference of serum MDA . Timepoint: Before and after intervention. Method of measurement: Serum level.;Mean difference of ESR. Timepoint: Before and after intervention. Method of measurement: Photo-metric.;Mean difference fatigue score in fatigue questionnaire. Timepoint: Before and after intervention. Method of measurement: Fatigue questionnaire.;Mean difference of clinical symptoms. Timepoint: Before and after intervention. Method of measurement: DAS-28 questionnaire.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Zamzam Paknahd

Esfahan University of Medical Sciences

paknahad@hlth.mui.ac.ir+98 31 3792 3166

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026