Assessment of intrauterine injection of human Chorionic Gonadotropin (hcg) before transferring of Frozen-Thawed embryo on Implantation and clinical pregnancy rate

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014110612146N5

Enrollment

100

Registered

2014-12-04

Start date

2014-11-19

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female Infertility. Female infertility

Interventions

Intervention 1: In the intervention group, five thousand units of hCG in a vial with 0.4 ml of ISM1 mixed media and 40 microliter of which is equivalent to 500 IU hCG injected through the catheter int

Treatment - Drugs

In the intervention group, five thousand units of hCG in a vial with 0.4 ml of ISM1 mixed media and 40 microliter of which is equivalent to 500 IU hCG injected through the catheter into the uterus. Se

In the control group, if endometrial thickness to achieve eight millimeters or more injections of progesterone injected intramuscularly at a dose of fifty milligrams per day.Transfer Eight-cell embryo

Eligibility

Sex/Gender

Female

Age

No minimum to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients younger than 40 years old who underwent treatment protocols for IVF (ISCT) however, due to the unsuitable conditions in their endometrium embryo transfer cycles done in fresh or pregnancy occurred; patients with frozen embryos. Exclusion criteria: patients with a history of uterine surgery; recurrent abortions; hydrosalpinges; endometriosis and endometriomas.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Positive Pregnancy Test. Timepoint: Two weeks after embryo transfer. Method of measurement: Test ßhCG.	—

Secondary

Measure	Time frame
Gestational sac. Timepoint: Three weeks after embryo transfer. Method of measurement: Primary vaginal ultrasound.;The number of bags. Timepoint: Three weeks after embryo transfer. Method of measurement: Primary vaginal ultrasound.;Fetal pole. Timepoint: Three weeks after embryo transfer. Method of measurement: Primary vaginal ultrasound.;Embryo heart. Timepoint: Three weeks after embryo transfer. Method of measurement: Primary vaginal ultrasound.	—

Measure

Time frame

Gestational sac. Timepoint: Three weeks after embryo transfer. Method of measurement: Primary vaginal ultrasound.;The number of bags. Timepoint: Three weeks after embryo transfer. Method of measurement: Primary vaginal ultrasound.;Fetal pole. Timepoint: Three weeks after embryo transfer. Method of measurement: Primary vaginal ultrasound.;Embryo heart. Timepoint: Three weeks after embryo transfer. Method of measurement: Primary vaginal ultrasound.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Farzadi Laaya

Tabriz University of Medical Sciences

lahroudin@gmail.com; wrhrcenter@gmail.com+98 41 3556 9543

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026