Surrvey The effect of probiotic supplementation on weight changes, hormonal and metabolic levels in women with polycystic ovary syndrome

Surrvey the effect of Probiotic Supplement on antropometric indexes, hormonal and metabolic parameters, clinical symptoms and serum apelin level in women with polycystic ovary syndrom --------------------------------------------------------------------------------

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014110515536N2

Enrollment

Registered

2015-12-19

Start date

2015-09-25

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Poly cystic ovary syndrom. E28.2

Interventions

Intervention 1: control group:plasebo,capsule 500mg,2times/day,for12 week. Intervention 2: Intervention group:Lactocare probiotic supplement(Zist takhmir company), oral Capsule 500mg,2times/day,for 12

Treatment - Drugs

control group:plasebo,capsule 500mg,2times/day,for12 week

Intervention group:Lactocare probiotic supplement(Zist takhmir company), oral Capsule 500mg,2times/day,for 12 week

Eligibility

Sex/Gender

Female

Age

19 Years to 37 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: women 37-19 years old; Obese and overweight (BMI=25); Diagnosis of polycystic ovary syndrome (PCOS diagnosis based on the Rotterdam criteria 2003) Non-inclusion criteria: history of systemic and chronic diseases; smoking; The use of some medications, supplements and diets less than two months from the start of the study Exclusion criteria: pregnancy; During the study complained of infertility

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Body mass index. Timepoint: Before and 3 month after the intervention. Method of measurement: Calculated by the formula.;Insulin resistance and insulin sensitivity. Timepoint: Before and 3 month after the intervention. Method of measurement: Calculated by the formula.;Plasma apelin level. Timepoint: Before and 3 month after the intervention. Method of measurement: Laboratory method.	—

Secondary

Measure	Time frame
Lipid profiles level. Timepoint: Before and 3 month after the intervention. Method of measurement: Laboratory method.;Sex hormones level. Timepoint: Before and 3 month after the intervention. Method of measurement: Laboratory method.;Changing clinical symptoms. Timepoint: Before and 3 month after the intervention. Method of measurement: Through questionnaires and clinical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElham Karimi

Tehran university of Medical Sciences/School of Nutritional Sciences and Dietetics

karimi_7997@yahoo.com+98 21 8895 5897

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 27, 2026