The Topical Effect of Grape Seed Extract Cream on Wound Healing

The Topical Effect of Grape Seed Extract 2% Cream on Surgery Wound Healing

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014110314190N6

Enrollment

Registered

2015-05-11

Start date

2012-09-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgical Site Infection and Wound Healing. Local infection of skin and subcutaneous tissue, unspecified

Interventions

Intervention 1: Intervention group: patients treated Grape Seed Extract 2% Cream and were followed for 3 weeks. Intervention 2: Control group: patients treated with placebo and were followed for 3 w

Treatment - Drugs

Intervention group: patients treated Grape Seed Extract 2% Cream and were followed for 3 weeks.

Control group: patients treated with placebo and were followed for 3 weeks.

Eligibility

Sex/Gender

All

Age

14 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: comprised skin lesions such as skin tag and mole on the neck, trunk and limbs (except for face); age between 14 and 50 years; clinical benignity of the lesion; size of the lesion larger than 3mm and smaller than1cm. Exclusion Criteria: having any underlying diseases, immunosuppressant or other certain medications; pregnancy or lactation; smoking or any long-term drug use; and having concurrent malignancy.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Surface area of the skin. Timepoint: Then the patients were visited on the 3rd, 7th, 10th, 14th, and 21st day. Method of measurement: In all the patients, transparent sheet was used to measure the surface area of the sample and the shape of the lesion was graphed. Furthermore, in every visit the patients’ wounds were photographed with an 8 MP Cannon camera. On the first day, wound level was considered 100% and improvement 0%, the next days, wound level and the rate of improvement were assessed and registered.	—

Measure

Time frame

Surface area of the skin. Timepoint: Then the patients were visited on the 3rd, 7th, 10th, 14th, and 21st day. Method of measurement: In all the patients, transparent sheet was used to measure the surface area of the sample and the shape of the lesion was graphed. Furthermore, in every visit the patients’ wounds were photographed with an 8 MP Cannon camera. On the first day, wound level was considered 100% and improvement 0%, the next days, wound level and the rate of improvement were assessed and registered.

—

Secondary

Measure	Time frame
Wound infection. Timepoint: At the end of the study. Method of measurement: clinical findings and wound culture.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Maryam foroozan

Ahvaz Jundishapur University of Medical Sciences

foroozan.m@ajums.ac.ir+98 613336754

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026