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Reducig pain on Injection of IV drug

Comparing the efficacy of Granisetron and Lidocaine on reducing the pain on injection of Etomidate: a double blind clinical trial.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201411025175N19
Enrollment
30
Registered
2014-12-07
Start date
2014-11-09
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The effect of Granisetron and Lidocaine on reducing the pain on injection of Etomidate in patients under elective laparoscopic cholecystectmy.. Unspecified complication following infusion, transfusion and therapeutic injection

Interventions

Intervention 1: Intervention 1: 2 mL of Lidocaine was administerd to a vein on dorsum of one hand and one minute later the elastic band was opened and 2mg (1 ml) Etomidate at the same rate was admini
Prevention
Intervention 1: 2 mL of Lidocaine was administerd to a vein on dorsum of one hand and one minute later the elastic band was opened and 2mg (1 ml) Etomidate at the same rate was administerd.
Intervention 2: 2ml of Granisetron was administered to a vein on dorsum of the other hand at the same time and one minute later the elastic band was opened and 2mg (1 ml) Etomidate at the same rate w

Sponsors

Tehran University of Medical Sciences
Lead Sponsor
Tehran University of Medical Sciences
Collaborator

Eligibility

Sex/Gender
All
Age
25 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: American Society of Anesthesiologists (ASA) physical status class I or II; age between 25-60, patients who were candidated for elective laparoscopic cholecystectomy; consent of patients and filling an informed written consent; patients without a history of thrombophlebitis or vascular disease, chronic pain; diabetes mellitus; not to be addicted. Exclusion criteria: If patient can not corporate because excess level of sedation; unsuccessful intravenous catheterization, dispensing with participation in study; any drugs taken other than what prescribed in protocol.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: 2 minutes after injection. Method of measurement: Numeric Rating Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ali Movafegh

Dr. Shariati Hospital

movafegh@sina.tums.ac.ir+98 21 8490 2372

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026