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Comparison of Dexamethasone and Ibuprofen following oral surgery

Comparison of oral administration of dexamethasone and Ibuprofen to reduce pain in patients after periodontal surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201411025029N3
Enrollment
40
Registered
2015-05-30
Start date
2014-12-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic periodontitis. Chronic periodontitis : simplex periodontitis

Interventions

Intervention 1: Ibuprofen(Daana pharma Co production) 400 mg oral, 1 hour before surgery and 400 mg every 8 hours after surgery. Intervention 2: Dexamethasone(Iran hormone) tablets 8 mg oral, 1 hour b
Treatment - Drugs
Ibuprofen(Daana pharma Co production) 400 mg oral, 1 hour before surgery and 400 mg every 8 hours after surgery
Dexamethasone(Iran hormone) tablets 8 mg oral, 1 hour before surgery

Sponsors

Vice chancellor for research, Dental school of Hamadan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Patients with moderate to severe chronic periodontitis and requires surgical debridement flap in 4 quadrants Exclusion Criteria: Patients with systemic disease, pregnant and breast feeding patients, patients with allergy to drugs, patients using antibiotic or pain relief drugs, patients with risk of infective endocarditis.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain of patients after periodontal surgery. Timepoint: Completed questionnaires every hour for 8 hours the first day and 3 times a day (morning, afternoon, evening) at 3 days after surgery. Method of measurement: NRS-101, VRS-4 questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDR Shahram Sharifi

School of Dentistry Hamadan University of Medical science

shahramsharifi60@yahoo.com+98 81 3838 0262

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026