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Effect of Chlorhexidine gel in diabetic and gum disease patients

Clinical and metabolic changes after subgingival insertion of xanthan-based chlorhexidin gel in type 2 diabetic patients with chronic periodontitis.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201411023690N5
Enrollment
33
Registered
2015-07-17
Start date
2014-12-09
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic periodontitis. Chronic pericoronitis Periodontitis: NOS complex simplex

Interventions

Intervention 1: chart completion, scaling and brushing by handheld devices, ultrasonic and Rabrkp and paste pumice in treatment during, injected the chlorhexidin within gingiva. Intervention 2: chart
Treatment - Drugs
chart completion, scaling and brushing by handheld devices, ultrasonic and Rabrkp and paste pumice in treatment during, injected the chlorhexidin within gingiva
chart completion, scaling and brushing by handheld devices, ultrasonic and Rabrkp and paste pumice

Sponsors

Vice Chancellor for research of Tabriz University of Medical Sciences, School of Dentistry, Tabriz,
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: presence of type 2 diabetes ; HbA1c = 6.0% ; Clinical Diagnosis of moderate generalized chronic periodontists defined by loss of clinical attachment more than 3mm and bone loss more than 30% ; Presence of more than 10 teeth per dental arch, excluding third molars ; No previous periodontal treatment taken ; signing informed consent, and commitment to post treatment follow-up visits ; no modification in medication for two months, before or during the study exclusion criteria: Presence of systemic disease that could influence the course of periodontal disease ; Intake of anti-inflammatory antibiotics for four weeks before the study ; current smokers or ex-smokers of <5 years ; Pregnancy or intention to be pregnant during the six months of study ; Intake of periodontal treatment in 3 months ago ;

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
HbA1c. Timepoint: Before the experiment, three months after the intervention, six months after the intervention. Method of measurement: Examination.

Secondary

MeasureTime frame
Fast Blood Sugur (FBS). Timepoint: Befoer the experiment (Baseline) , 3 months after the intervention, 6 month after the intervention. Method of measurement: Examination.;Clinical attachment level (CAL). Timepoint: Befoer the experiment (Baseline) , 3 months after the intervention, 6 month after the intervention. Method of measurement: with periodontal prob from CEJ to pocket depth.;Probing depth (PD). Timepoint: Befoer the experiment (Baseline) , 3 months after the intervention, 6 month after the intervention. Method of measurement: with periodontal prob.;Plaque Index. Timepoint: Befoer the experiment (Baseline) , 3 months after the intervention, 6 month after the intervention. Method of measurement: Disclosing tablets.;Bleeding Index (BI). Timepoint: Befoer the experiment (Baseline) , 3 months after the intervention, 6 month after the intervention. Method of measurement: observe.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Masoumeh Faramarzi

Gum disease and tooth Research Center, School of Dentistry, Tabriz

faramarzim@tbzmed.ac.ir+98 41 3335 5965

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026